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Justia Patents US Patent Application for Malononitrile Compounds for Controlling Animal Pests Patent Application Application Malononitrile Compounds for Controlling Animal Pests Oct 9, The invention relates to the use of a compound of formula I or a salt thereof for combating animal pests, where the symbols and indices are defined in the specification. Provisional Application No. Animal pests destroy growing and harvested crops and attack wooden dwelling and commercial structures, causing large economic loss to the food supply and to property. While a large number of pesticidal agents are known, due to the ability of target pests to develop resistance to said agents, there is an ongoing need for new agents for combating animal pests. In particular, animal pests such as insects and acaridae are difficult to be effectively controlled. However, it is a continuing objective to provide further pesticidal compounds which, at least in some aspects, offer advantages over the known compounds.

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This chapter is an attempt to summarize my work of 30 years in developing the company from a small side activity to a world leading company in the field of patch testing products currently providing products to around 90 countries. Dedication and acknowledgments by Bo Niklasson, founder and president of Chemotechnique Diagnostics I want to dedicate this chapter to my dear wife Marie with a lot of love, she has given me faithful support and encou- ragement since the start of the company, a great inspiration for me and a discus- sion partner in strategic planning on many occasions.

Without her support the company would not exist today. In the chapter I mention persons that have been important and related to 2 for the diagnosis of contact allergy the business in many different ways, I will most likely forget some as my me- mory not always serves me and therefore I take the opportunity to apologize for this already in the beginning of the chapter.

My background within Chemistry and Biomedicine, later followed by Dermatology courses as well as my expe- rience from the clinical work, gave me insight and means to develop a number of different test series related to various occupations and exposures to a wide variety of haptens.

These substances were found in products handled at the work place in many different industrial environments. Numerous contacts with companies producing such products providing information on ingredi- ents facilitated the selection of substances to be investigated. An important aspect of patch testing is the knowledge how to prepare the patients own products brought in from the work place.

I was offered the opportunity to share my experience in this field by professor Jere Guin in his book Practical Contact Dermatitis from Mc Graw Hill as well as providing hapten in- formation in Handbook of Occupational Dermatology by Kanerva, Wahlberg and Maibach in the year One important compound that we discovered many contact allergies to was the preservative with the brand name Kathon CG manufactured by Rohm and Haas company in USA.

This became a quite sensitive issue and the chief toxicologist from the company visited us to dis- cuss the matter. Other interesting compounds causing outbreaks of allergic contact dermatitis were various acrylates in the printing industry.

The actual reason for starting the company was related to a Swedish multicen- ter clinical trial of a new test series of haptens for diagnosing contact allergy in dental staff and patients undergoing dental treatments. The name of the series for the selected haptens was "Dental Screening series". The clinics had to get the material for testing and as such the possibility and proper time to 3 Chemotechnique D iagnostics prepare the material at the clinic was simply not available.

The result after discussing the project with the hospital legal department was to provide the material through a company instead of the clinic. The research work investigating the dental screening series was finalized and resulted in a publication in Contact Dermatitis. The development of the company.

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EPA Contract No. However, there remain environmental problems that cannot be effectively solved only through traditional, compartmentalized, command-and- control approaches, for example, non-point source pollution, decline of biodiversity, and urban sprawl. Recognizing the need for more holistic and integrated approaches to improving environmental quality, in the s EPA instituted a more place-based approach to environmental protection. These methods encourage geographic targeting of locations in need of protection or environmental improvements to reduce human health risks in an equitable way environmental justice and to protect and improve ecosystems and the services they provide. This report focuses on approaches in use or under development in the ten EPA Regions. It also identifies a few selected approaches under development by other entities. The Office of Sustainable Ecosystems and Communities OSEC sponsored development of this report to assist the EPA Regions in sharing information on methods and data sources that can be used now or are being developed for future use in ecosystem targeting.

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This chapter is an attempt to summarize my work of 30 years in developing the company from a small side activity to a world leading company in the field of patch testing products currently providing products to around 90 countries. Dedication and acknowledgments by Bo Niklasson, founder and president of Chemotechnique Diagnostics I want to dedicate this chapter to my dear wife Marie with a lot of love, she has given me faithful support and encou- ragement since the start of the company, a great inspiration for me and a discus- sion partner in strategic planning on many occasions. Without her support the company would not exist today. In the chapter I mention persons that have been important and related to 2 for the diagnosis of contact allergy the business in many different ways, I will most likely forget some as my me- mory not always serves me and therefore I take the opportunity to apologize for this already in the beginning of the chapter. My background within Chemistry and Biomedicine, later followed by Dermatology courses as well as my expe- rience from the clinical work, gave me insight and means to develop a number of different test series related to various occupations and exposures to a wide variety of haptens. These substances were found in products handled at the work place in many different industrial environments. Numerous contacts with companies producing such products providing information on ingredi- ents facilitated the selection of substances to be investigated.

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